Transmembrane Prediction

Predict transmembrane spanning regions of proteins

Transmembrane Plugin

Predict transmembrane helices using Transmembrane Hidden Markov models (TMHMM). Output can be displayed as a graph or saved as annotations on the sequence.

By Prof. Marc Suchard

Quick Start

Install the plugin by downloading the gplugin file and dragging it in to Geneious or use the plugin manager in Geneious (under Tools - Plugins in the menu).

Once installed, select a protein sequence and choose Annotate & Predict - Predict Transmembrane Regions from the menu to annotate predicted regions on the sequence. To view results as a graph, turn on Transmembrane Prediction in the Graphs section of the controls to the right of the Sequence view.


1.0.2 (02 May 2022) – Download for Geneious 2020.0

– Fixed a crash when sequence names were empty

1.0.1 (14 Nov 2019) – Download

– Replace Windows binaries with newly-built copies that can output posterior probabilities

1.0.0 (02 Aug 2019) – Download

– Upgraded modhmms to 1.1.1

0.9 (07 Apr 2011) – Download

– Fixed compatibility with linux

0.7 (18 Sep 2008) – Download

– More informative annotations

Get started with Geneious today