Get Started with Geneious Biologics

Course Content

Activate Your Licence and Add Users

Learn how to activate your organization, add users, and share workspaces in Geneious Biologics.
LENGTH 2 minutes

Navigate the Platform and Upload Files

Navigating the platform, uploading data, and making, sharing, and moving folders in Geneious Biologics.
LENGTH 2 minutes

Pre-Process Sanger Sequences

Pre-process your Sanger antibody sequences and prep them for analysis, including batch and automatically batch assembling sequences.
LENGTH 3 minutes

Pre-Process NGS Sequences

Pair and merge large antibody sequence datasets produced by NGS, and a brief overview of processing barcoded sequences.
LENGTH 3 minutes

Using the Antibody Annotator Tool

Use the annotator tool to annotate regions of interest, identify and annotate germline gene differences and liabilities on your sequences, and cluster sequences.
LENGTH 2 minutes

Understanding Your Results in Graphs and Clusters

Understand the pipeline report, navigate the graphs tab, and understand and visualize clusters in your data in Geneious Biologics.
LENGTH 2 minutes

Understanding Your Results in Data Tables

Learn how to navigate the Sequence Viewer, view annotated sequences and filter sequences in Geneious Biologics.
LENGTH 2 minutes

Adding Bioassay Data to Annotated Sequences

Learn how to add bioassay data to annotated sequences and create and use labels in Geneious Biologics.
LENGTH 2 minutes

Align Annotated Sequences

Align your annotated sequences in Geneious Biologics to quickly visualize how similar they are at specific regions.
LENGTH 1 minute

Exporting and Extracting Sequences

Learn how to extract and export your data. Export representative sequences from clusters, extract and recluster, and export graphs and images.
LENGTH 3 minute

Common Questions About Geneious Biologics

What is Geneious Biologics?

Geneious Biologics is cloud-based software for antibody discovery and engineering that analyzes antibody sequence data to identify, optimize, and prioritize therapeutic candidates. It supports Sanger, NGS, and single-cell datasets and annotates antibody types including mAb, Fab, scFv, VHH, TCR, and VH/VL pairs in a single collaborative workspace.

How does the Antibody Annotator work in Geneious Biologics?

The Antibody Annotator assigns CDR/FR regions from germline or custom databases, identifies germline gene differences, and flags sequence liabilities. Results are clustered by sequence identity and displayed in an interactive table with filterable columns, graphs, and alignment views.

What does the Getting Started with Geneious Biologics video series cover?

The series covers ten short videos spanning the full initial workflow: account activation and user management, platform navigation and file upload, Sanger and NGS sequence pre-processing, antibody annotation, results interpretation in graphs and data tables, adding bioassay data, sequence alignment, and exporting data.

Can I integrate bioassay data with sequence analysis in Geneious Biologics?

Yes. Bioassay data can be imported from Excel or CSV files and merged with annotated sequences. Once integrated, assay values are searchable and filterable alongside sequence properties, and can be visualized in alignments and cluster graphs to support candidate prioritization.

What sequence data types does Geneious Biologics support?

Geneious Biologics accepts Sanger, NGS, and single-cell antibody sequence datasets. Files can be uploaded by drag-and-drop or via the Upload button, and the platform includes pre-processing pipelines for paired-end merging, batch Sanger assembly, barcode separation, and UMI deduplication.

How is data shared and kept secure in Geneious Biologics?

Geneious Biologics is a cloud-based platform with folder-level sharing and permission controls. Organizations can collaborate in a shared workspace, and the platform holds ISO 27001:2013 certification for information security management.

More Geneious Academy

Deepen your understanding of key concepts in antibody discovery and master the broad range of Geneious Biologics tools with this in-depth video series.
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