Geneious Biologics - June 2020

Biologics June 2020 was released on June 09, 2020.

Dynamic Reporting

You can now create custom reports from your analysis results. These reports can include statistics tables, graphs, images of your sequences, and your own notes. Reports are saved in Geneious Biologics as a record, and can also be exported as PDFs to store in ELNs or other record keeping systems.

Read more about the full functionality of Dynamic Reports.

Automated Sequence Repair

In standard Ig-like antibodies, sequence quality can often be low in certain regions, such as at the beginning of FR1 regions or the end of FR4. Sometimes these regions can even be truncated, making extracting a viable candidate sequence difficult. Our latest pipeline "Automated Sequence Repair" aims to solve this problem for you by replacing poor quality or missing regions with bases from their closest germline match. This is just a first alpha version, and we hope to cover more repair scenarios in the future.

Read the full details on Repairing Low-quality Sequences after Annotation.

Upload Improvements

We are continuing to improve the reliability and convenience of uploading files. In particular, we have enhanced our upload table to show more information about your upload, including specific error messages that should help if anything unexpected happens.

We also have a new upload FAQ and troubleshooting guide.

Our latest infrastructure improvements also include some significant speed improvements for upload of individual sequences. For example if you are uploading 96 .ab1 files, your upload and import time should now be greatly improved. Don't worry we haven't forgotten larger datasets either, improvements for upload of NGS-size files are currently in the works.

Database Types

We have received feedback that creating new reference databases can be confusing, and so we are making some changes to help streamline this process. The first change is to introduce Reference database "types". These correspond to the different ways reference databases can be used, such as the crucial Germline databases for Antibody Annotator.

A full description of the different types is available in the article Understanding Reference Databases. From now on you will need to specify a type when creating a new database. Please feel free to ask if you are unsure which type this should be.

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