Antibody NGS Data Analysis

Geneious Biologics’ powerful cloud computing platform quickly and accurately analyzes NGS data, helping you better understand the diversity and quality of your antibody libraries and immune repertoires. Engineered to intelligently manage and process NGS data, Geneious Biologics provides intuitive visualization tools that accelerate identification of therapeutic antibody candidates. Geneious Biologics brings together advanced analytics tools in a user friendly interface to improve accuracy and increase success in therapeutic antibody discovery.

Analyze
  • Analyze millions of NGS raw antibody sequences in minutes
  • QC/trim, assemble, merge paired end data
  • Preview, annotate and compare NGS sequences with no manual intervention
  • Automatically validate sequences – define your own rules
  • Search and filter on large NGS datasets
  • Cluster and index annotated NGS sequences
  • Show cluster diversity and region length plots
Visualize
  • Compare NGS data sets and plot results of germline, diversity and region frequency
  • Inspect individual sequences in large data sets using the intuitive sequence viewer
  • Identify outliers, see cluster and sequence distribution with scatter plots
  • Visualize interesting clusters and sequences with sequence viewer
  • Look at amino acid variability with (aa) composition plots
  • Show relationships between genes in sequences with heat map graphs
  • Leverage versatile stack bar charts/histogram capability to quickly understand trends
Discover
  • Spot high-level trends in large scale antibody NGS datasets
  • Drill down into individual sequences
  • Achieve deep understanding of your antibody data
  • Accelerate precision antibody discovery
Often you have to shoehorn a software solution into your process, the adaptability of Geneious Biologics was something we liked a lot. Once we knew what we could do with Geneious Biologics there was no other viable option.
Liuhong Chen, Ph.D.Discovery Biology Team Leader at Bicycle Therapeutics