Effortless Visualization and Navigation
With just a click, get the visualization you need for the data you have in front of you. Annotated genomes, circular genomes, mapped reads, contigs are all displayed in our highly customizable sequence view. Choose coloring schemes, graphs and tracks of additional annotations to display, then use dynamic annotation searching and location jumping to find what you’re looking for.
Powerful SNP Variants Analysis
Find SNP/Variants with either the versatile Geneious algorithm or well known FreeBayes. If you have variant calls from an external pipeline or provider, simply drag in a VCF. Identify novel variants by programmatic comparison with known variants or sort and filter using our dynamic tabular view then see the genomic context by switching to the synchronized sequence view.
Simple RNA-Seq Expression Analysis
Calculate expression levels from mapped reads then perform pairwise comparison between samples to identify differentially expressed genes. Without any expertise in the statistical programming language, R, use the industry standard DESeq2 package to compare expression between two conditions, each with replicate samples.
Switch to the PCA Plot tab to check the quality of your data using principal component analysis then switch to the interactive volcano plot to spot genes of interest. After selecting a gene in the volcano plot you can jump straight to it in the sequence view where all genes have heatmap coloring based on differential expression.
Download a free trial and one of our tutorials to get to grips with the functionality of Geneious interactively.
Learn to calculate normalized expression measures from RNA-Seq data. Measure RPKM, FPKM and TPM on datasets from two different sample conditions then calculate differential expression between the two samples.
Learn how to use DESeq2 in Geneious to compare expression levels for two sample conditions with replicates.
Explore a pipeline in Geneious which allows accurate identification and analysis of low concentrations of ZIKV from high-throughput metagenomic data proceeding from a patient with suspected infection.
Geneious is an absolutely beautiful package to work with. We love it and we are telling everyone about it.
We bought Geneious to work with Illumina datasets, and were delighted in its power and intuitive interface. It really takes advantage of multi-core processing, assembling tens of millions of reads to a reference sequence in minutes on a desktop system. And the strong user community means that help is not far off—hours after I posted a thread about a task I wanted to do, another user had a perfect solution! Finally we have an integrated system at an affordable price for all our DNA sequence analysis needs. Thanks, Geneious.
Geneious is the perfect combination of ease-of-use and bioinformatic refinement. Students easily grasp many of the concepts of bioinformatics because the sequence data is visualized so well. As researchers, we routinely use its functionality to perform data analysis on real data.